Report Title: Experimental Methods of Neuropsychopharmacology of Traditional Chinese Medicine

Time: September 15, 2022 (Thursday) 13:30-15:30

Venue: Multipurpose Hall, Wang Changlai Building, School of Medicine

Speaker: Liu Xinmin

Personal profile:

Liu Xinmin, consultant in Traditional Medicine of World Health Organization, researcher/principal scientist of Institute of Drug Discovery Technology of Ningbo University, and doctoral tutor; chairman of Committee of Identification and Evaluation for Experimental Animal Models, Chinese Association for Laboratory Animal Sciences; director of Sino-Pakistan Cooperation Center on Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine; vice chairman of National Science and Technology Innovation Alliance for Food and Medicine Industry; member of Medical Expert Panel of National Manned Space Program. Liu has been engaged in research on the neuropsychopharmacology of traditional Chinese medicine based on animal behavior experiments, research on the protection of traditional Chinese medicine from stress damage of aerospace special factor environment, and strategic research on internationalization and modernization of traditional Chinese medicine for over thirty years.

Liu has won more than 30 projects such as National Major Project of New Drug Innovation Investment and Key Project of Cooperation on Traditional Chinese Medicine, more than 10 awards from the state, ministries and commissions, more than 10 national innovation patents, and 6 certificates of Canada natural health products. Liu has published more than 80 high-level papers as the first or corresponding author. Liu has cultivated more than 60 post-graduates and doctoral graduates. In close cooperation with the team of General Chen Shanguang of Chinese Astronaut Center for more than 20 years, Liu has developed several sets of highly automated and intelligent animal behavior experimental facilities for rats and mice, and established a complete, fully functional, objective and standard technical system for learning memory, depression and anxiety behavior experiments. Liu has established long-term and stable cooperative relations with famous universities and colleges in countries along “the Belt and Road”, such as Pakistan, United Arab Emirates and Portugal, in the research and development of traditional Chinese medicine (herbs), cultivation of postgraduates, and international registration of products. Liu is a senior expert in the World Health Organization, Ministry of Science and Technology, and Strategic Planning of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine.

Content:

Liu introduced the definition, connotation and denotation of neuropsychopharmacology of traditional Chinese medicine, and described the classification of Chinese neuropsychiatric drugs, and the position and role of animal behavior experiment methods in the research of neuropsychopharmacology. Based on more than 30 years of cooperation between this team and the team of researcher Chen Shanguang (now the deputy chief engineer of the National Manned Space Program) of Chinese Astronaut Center, as well as the experience in the research on brain function injury caused by stress in aerospace special factor environment and its protection of traditional Chinese medicine, Liu detailed the detection devices and evaluation index systems involved in the pharmacological experiments of traditional Chinese medicine for improving learning memory, anti-depression and anti-anxiety, sedation and hypnosis, and anti-fatigue. Meanwhile, Liu also summarized the animal models, and pharmaceutical effect detection methods and animal models commonly used in the research of neuropsychopharmacology of traditional Chinese medicine, and put forth key points for attention in the research of neuropsychopharmacology of traditional Chinese medicine.